Factors Associated with Antigen HBs Seroconversion among Blood Donors in Ouagadougou from 2008 to 2017

Introduction: The risk of transmission pathogens such as hepatitis B virus threatens the safety transfused patients especially in high endemic areas. aim this study was to determine incidence and factors associated with surface antigen (HBsAg) seroconversion blood donors at Regional Blood Transfusion Centre Ouagadougou. Methods: A retrospective cohort voluntary non-remunerated (VNRBD), conducted from 2008 2017. Data on HBsAg were collected. Kaplan-Meier method Log-Rank test used estimate survival curves. Cox’s regression identified seroconversion. Results: Of 23,494 donors, 559 had number donor years 58,637.50 HBV rate 9.53 per 1000 years. median time 75.73 months extremes 2.7 107.12 months. 1.30 times higher among aged 21 24 old (p = 0.007) 2.49 those over < 0.0001) than under old. Female 1.11 more likely seroconvert male 0.33). Donor residence not significantly (Hazard ratio 1.12; p 0.36). decreased donations 0.58; 0.006). Conclusion: remains which could have a negative impact transfusion safety. age AgHBs